0 Prenatal DHA reduces early preterm birth low birth weight

University of Kansas researchers have found that the infants of mothers who were given 600 milligrams of the omega-3 fatty acid DHA during pregnancy weighed more at birth and were less likely to be very low birth weight and born before 34 weeks gestation than infants of mothers who were given a placebo. This result greatly strengthens the case for using the dietary supplement during pregnancy.

The results are from the first five years of a 10-year, double-blind randomized controlled trial to be published in the April issue of the American Journal of Clinical Nutrition. It is also available online. A followup of this sample of infants is ongoing to determine whether prenatal DHA nutritional supplementation will benefit children’s intelligence and school readiness.

“A reduction in early preterm and very low birth weight delivery could have clear clinical and public health significance,” said Susan Carlson, A.J. Rice Professor of Dietetics and Nutrition at the KU Medical Center, who directed the study with John Colombo, KU professor of psychology and director of the Life Span Institute.

“We believe that supplementing U.S. women with DHA could safely increase mean birth weight and gestational age to numbers that are closer to other developed countries such as Norway and Australia,” she said.

DHA (docosahexaenoic acid) occurs naturally in cell membranes with the highest levels in brain cells, but levels can be increased by diet or supplements. An infant obtains DHA from his or her mother in utero and postnatally from human milk, but the amount received depends upon the mother’s DHA status.

“U.S. women typically consume less DHA than women in most of the developed world,” said Carlson.

During the first five years of the study, children of women enrolled in the study received multiple developmental assessments at regular intervals throughout infancy and at 18 months of age. In the next phase of the study, the children will receive twice-yearly assessments until they are 6 years old. The researchers will measure developmental milestones that occur in later childhood and are linked to lifelong health and welfare.

Previous research has established the effects of postnatal feeding of DHA on infant cognitive and intellectual development, but DHA is accumulated most rapidly in the fetal brain during pregnancy, said Colombo. “That’s why we are so interested in the effects of DHA taken prenatally, because we will really be able to see how this nutrient affects development over the long term.”

0 Alpha Lipoic Acid Lowers Blood Pressure and Reduces Stroke Risk

(Article first published as Super Nutrient Lowers Blood Pressure and Reduces Stroke Risk on Technorati.)

Slowly rising blood pressure as we age places millions of Americans at increased risk for heart attack and stroke. Medical practitioners and Big Pharma think the answer is prescribe a host of different pharmaceuticals until a magical number is achieved artificially. Research has rapidly emerged to demonstrate that reaching a normal blood pressure using drugs is not the same as lowering blood pressure naturally.

In fact, using drugs to lower blood pressure can contribute to a host of damaging side effects including death. Fortunately you can take advantage of nature`s treasure of antioxidants from fruits and vegetables and supplement with lipoic acid to dramatically lower your risk of heart attack and stroke.

Protein Damage Contributes to High Blood Pressure

For the first time, researchers have discovered the actual underlying cause of high blood pressure and the best way to alleviate the problem at its source. The result of a study published in the journal Nature demonstrated that a key regulatory protein that controls blood pressure is damaged by the normal wear and tear caused by free radicals. The protein angiotensinogen becomes damaged through free radical assault and leads to hypertension.

Researchers found that a low antioxidant status was indicative of increased blood pressure. Insufficient circulating antioxidants allow damage to angiotensinogen protein molecules and loss of blood pressure regulation. The study determined that simply increasing antioxidant status was not enough to fully lower blood pressure readings and found that other mitigating factors such as stress, being overweight, and insulin resistance generated high levels of free radical damage. When these factors were addressed and controlled, increased intake of antioxidants from natural food sources and supplementation effectively lowered blood pressure levels.

Antioxidants Lower Risk of Stroke by 60%

Stroke is a leading cause of disability and mortality in western society, largely due to damage to the delicate vascular network and the movement of blood clots through the body. Free radicals cause the endothelial lining of delicate blood vessels to become unstable and inflamed, greatly increasing the risk of an ischemic stroke. A study released in the Journal of Nutrition found that individuals with the highest antioxidant status were 60% less likely to suffer from a stroke. Vitamin C alone was found to lower the risk by 40%.

Lipoic Acid Rejuvenates Antioxidant Status During Aging

The human body functions at an advanced metabolic rate and our cellular mitochondria generate large amounts of free radicals that wreak damage in the process. Mitochondria are the energy producing structures in each cell and are particularly vulnerable to free radical damage. Details of a study published in the Annals of the New York Academy of Science demonstrated how lipoic acid is able to prevent damage to the mitochondria by providing a powerful antioxidant shield to the cellular structure. They found the `R-lipoic acid` form to be most effective.

Energy production within our body generates large numbers of free radicals that are known to be the cause of aging and chronic conditions including heart disease, high blood pressure and stroke. In addition to controlling external factors such as stress, weight and insulin resistance, increasing antioxidant status from raw foods and supplements is shown to slow the aging process and dramatically lower the risk of disease.